behringer uphoria 404hd turns off when I switch software I'm using

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Example:


I'm using Pro Tools.  All is good with 404.


I close PT.


 


I open ZOOM to start a meeting.  Zoom does not "connect" to 404.


Or I open Itunes.    No Audio.  Itunes does not connect to 404.


 


Every time I switch programs (Itunes, Adobe Premiere, PT, Zoom) that I'm using.... I have to re-boot my computer.


Then if I open zoom (or other program) the 404 works.


 


Then if I try to go to another audio-using software (Itunes).... there's no audio.  I have to re-boot again.


Help?


Thanks in advance.