Key/Scale randomly changes during song.

Contributor - Level 2
During the playing of a song accompanied with guitar, the vocal harmonies go from sound great to bad. When I hold the harmony button down to check the key/scale, I see the key/scale in my view has changed to A#min1 or D#min1 or some other key. I need some help. The goal is for the harmonies to sound terrific throughout the entire song and not randomly change keys.
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